Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11110959 | 0.86 | MEN1 (0.41) | MEN1KMT2AALDH1A1HPGDCREBBP | |
| SCHEMBL9053520 | 0.85 | KMT2A (0.37) | MEN1KMT2AALDH1A1HPGDCREBBP | |
| SCHEMBL186143 | 0.84 | MEN1 (0.36) | MEN1KMT2AALDH1A1HPGDTP53 | |
| SCHEMBL3283171 | 0.83 | MEN1 (0.35) | MEN1KMT2ATHRBCYP4F2CYP4A11 | |
| SCHEMBL9115989 | 0.80 | MEN1 (0.40) | MEN1KMT2AALDH1A1CREBBPKDM4E | |
| SCHEMBL11114764 | 0.79 | MEN1 (0.42) | MEN1KMT2AALDH1A1HPGDCREBBP | |
| SCHEMBL10197050 | 0.79 | MEN1 (0.32) | MEN1KMT2ATHRBCYP4F2CYP4A11 | |
| SCHEMBL374442 | 0.78 | KMT2A (0.44) | MEN1KMT2AALDH1A1HPGDCREBBP | |
| SCHEMBL12336899 | 0.77 | MEN1 (0.41) | MEN1KMT2AALDH1A1HPGDCREBBP | |
| SCHEMBL11109111 | 0.77 | MEN1 (0.44) | MEN1KMT2AALDH1A1CREBBPKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2222740-B1 | FUNCTIONALIZED PHOTOREACTIVE COMPOUNDS | ROLIC AG (CH) | 2017-10-11 | — | — | EP | disclosed |
| EP-2222740-B1 | FUNCTIONALIZED PHOTOREACTIVE COMPOUNDS | ROLIC AG (CH) | 2017-10-11 | — | — | EP | disclosed |
| US-9499649-B2 | Functionalized photoreactive compounds | ROLIC AG (CH) | 2016-11-22 | — | — | US | disclosed |
| US-9499649-B2 | Functionalized photoreactive compounds | ROLIC AG (CH) | 2016-11-22 | — | — | US | disclosed |
| US-9499649-B2 | Functionalized photoreactive compounds | ROLIC AG (CH) | 2016-11-22 | — | — | US | disclosed |
| US-20100266821-A1 | FUNCTIONALIZED PHOTOREACTIVE COMPOUNDS | ROLIC AG (CH) | 2010-10-21 | — | — | US | disclosed |
| US-20100266821-A1 | FUNCTIONALIZED PHOTOREACTIVE COMPOUNDS | ROLIC AG (CH) | 2010-10-21 | — | — | US | disclosed |
| US-20100266821-A1 | FUNCTIONALIZED PHOTOREACTIVE COMPOUNDS | ROLIC AG (CH) | 2010-10-21 | — | — | US | disclosed |
| EP-2222740-A1 | FUNCTIONALIZED PHOTOREACTIVE COMPOUNDS | Rolic AG (CH) | 2010-09-01 | — | — | EP | disclosed |
| WO-2009080147-A1 | FUNCTIONALIZED PHOTOREACTIVE COMPOUNDS | ROLIC AG (CH) | 2009-07-02 | — | — | WO | disclosed |
| WO-2009080147-A1 | FUNCTIONALIZED PHOTOREACTIVE COMPOUNDS | ROLIC AG (CH) | 2009-07-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100266821-A1 | FUNCTIONALIZED PHOTOREACTIVE COMPOUNDS | ETV6, TERB1, VCL | MEN1 3607/4885KMT2A 1776/4885ALDH1A1 3835/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.