Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | ATM | Q13315 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.48 |
| ▸ | NSD2 | O96028 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31613393 | 0.83 | TSHR (0.59) | TSHRATMPOLBKDM4ESMN1; SMN2 | |
| SCHEMBL1631053 | 0.80 | TSHR (0.65) | TSHRATMPOLBKDM4ESMN1; SMN2 | |
| SCHEMBL10573841 | 0.79 | TSHR (0.54) | TSHRATMPOLBKDM4ESMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL20502504 | 0.78 | TSHR (0.62) | TSHRATMPOLBKDM4ESMN1; SMN2 | |
| SCHEMBL6320584 | 0.77 | KDM4E (0.61) | TSHRATMPOLBKDM4ESMN1; SMN2 | |
| SCHEMBL23308872 | 0.76 | TSHR (0.59) | TSHRATMPOLBKDM4ESMN1; SMN2 | |
| SCHEMBL27673212 | 0.76 | TSHR (0.59) | TSHRATMPOLBKDM4ESMN1; SMN2 | |
| SCHEMBL5632154 | 0.76 | TSHR (0.59) | TSHRATMPOLBKDM4ESMN1; SMN2 | |
| SCHEMBL2104486 | 0.76 | TSHR (0.59) | TSHRATMPOLBKDM4ESMN1; SMN2 | |
| SCHEMBL14252963 | 0.76 | TSHR (0.59) | TSHRATMPOLBKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120129678-A | Mitogen-activated protein kinase (MEK) inhibitors | 耐斯泰德医疗公司 | 2025-06-10 | — | — | CN | disclosed |
| EP-4551558-A2 | MITOGEN-ACTIVATED PROTEIN KINASE (MEK) INHIBITORS | Nested Therapeutics, Inc. (US) | 2025-05-14 | — | — | EP | disclosed |
| WO-2024010925-A2 | MITOGEN-ACTIVATED PROTEIN KINASE (MEK) INHIBITORS | NESTED THERAPEUTICS, INC. (US) | 2024-01-11 | — | — | WO | disclosed |