Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPE | Q05469 | 8/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 2/20 | 0.31 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.31 |
| ▸ | GRM8 | O00222 | 1/20 | 0.31 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.31 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26985696 | 1.00 | LIPE (0.39) | LIPEPTGS1PTGS2DGAT1EGFR | |
| SCHEMBL26985737 | 0.84 | PTGS1 (0.40) | LIPEPTGS1PTGS2 | |
| SCHEMBL30746484 | 0.84 | PTGS1 (0.40) | LIPEPTGS1PTGS2 | |
| SCHEMBL26985480 | 0.79 | EGFR (0.35) | LIPEEGFR | |
| SCHEMBL26985444 | 0.79 | SLC6A2 (0.37) | LIPEPTGS1PTGS2EGFR | |
| SCHEMBL30746522 | 0.79 | EGFR (0.35) | LIPEEGFR | |
| SCHEMBL30746489 | 0.78 | HTT (0.38) | DGAT1EGFRL3MBTL1 | |
| SCHEMBL26985465 | 0.78 | HTT (0.38) | DGAT1EGFRL3MBTL1 | |
| SCHEMBL30746551 | 0.76 | SLC22A12 (0.34) | PTGS1PTGS2EGFRL3MBTL1 | |
| SCHEMBL30746549 | 0.76 | SLC22A12 (0.34) | PTGS1PTGS2EGFRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4551558-A2 | MITOGEN-ACTIVATED PROTEIN KINASE (MEK) INHIBITORS | Nested Therapeutics, Inc. (US) | 2025-05-14 | — | — | EP | disclosed |
| WO-2024010925-A2 | MITOGEN-ACTIVATED PROTEIN KINASE (MEK) INHIBITORS | NESTED THERAPEUTICS, INC. (US) | 2024-01-11 | — | — | WO | disclosed |