Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 3/20 | 0.40 |
| ▸ | RAF1 | P04049 | 4/20 | 0.39 |
| ▸ | MAP2K1 | Q02750 | 4/20 | 0.39 |
| ▸ | BRAF | P15056 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.38 |
| ▸ | MAP2K5 | Q13163 | 1/20 | 0.38 |
| ▸ | FLT1 | P17948 | 6/20 | 0.34 |
| ▸ | KDR | P35968 | 6/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 4/20 | 0.34 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | EPHB2 | P29323 | 1/20 | 0.32 |
| ▸ | FLT4 | P35916 | 1/20 | 0.32 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26985286 | 1.00 | NUDT1 (0.40) | NUDT1RAF1MAP2K1BRAFCYP2C9 | |
| SCHEMBL26985030 | 0.94 | NUDT1 (0.41) | NUDT1RAF1MAP2K1BRAFCYP2C9 | |
| SCHEMBL30746401 | 0.94 | NUDT1 (0.41) | NUDT1RAF1MAP2K1BRAFCYP2C9 | |
| SCHEMBL30746529 | 0.92 | RAF1 (0.42) | NUDT1RAF1MAP2K1BRAFCYP2C9 | |
| SCHEMBL26984961 | 0.92 | RAF1 (0.42) | NUDT1RAF1MAP2K1BRAFCYP2C9 | |
| SCHEMBL30746525 | 0.89 | NUDT1 (0.38) | NUDT1RAF1MAP2K1BRAFCYP2C9 | |
| SCHEMBL26985123 | 0.89 | RAF1 (0.39) | NUDT1RAF1MAP2K1BRAFCYP2C9 | |
| SCHEMBL26985377 | 0.89 | NUDT1 (0.38) | NUDT1RAF1MAP2K1BRAFCYP2C9 | |
| SCHEMBL30746644 | 0.89 | RAF1 (0.39) | NUDT1RAF1MAP2K1BRAFCYP2C9 | |
| SCHEMBL30746520 | 0.84 | RAF1 (0.38) | NUDT1RAF1MAP2K1BRAFCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120129678-A | Mitogen-activated protein kinase (MEK) inhibitors | 耐斯泰德医疗公司 | 2025-06-10 | — | — | CN | disclosed |
| EP-4551558-A2 | MITOGEN-ACTIVATED PROTEIN KINASE (MEK) INHIBITORS | Nested Therapeutics, Inc. (US) | 2025-05-14 | — | — | EP | disclosed |
| WO-2024010925-A2 | MITOGEN-ACTIVATED PROTEIN KINASE (MEK) INHIBITORS | NESTED THERAPEUTICS, INC. (US) | 2024-01-11 | — | — | WO | disclosed |