SCHEMBL30747675

SCHEMBL30747675

CC(C)CN1CCC(Cn2nc(-n3cccn3)ccc2=O)CC1

nearest known ligand 0.37

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ ROCK2 O75116 1/20 0.34
▸ ROCK1 Q13464 1/20 0.34
▸ SLC34A1 Q06495 1/20 0.34
▸ KDM4A O75164 1/20 0.33
▸ KDM4B O94953 1/20 0.33
▸ KDM5C P41229 1/20 0.33
▸ KDM5B Q9UGL1 1/20 0.33
▸ MAPT P10636 1/20 0.33
▸ ALDH1A1 P00352 1/20 0.33
▸ LMNA P02545 1/20 0.33
▸ L3MBTL1 Q9Y468 1/20 0.33
▸ CACNA2D1 P54289 1/20 0.33
▸ HTR2C P28335 2/20 0.32
▸ KDM4E B2RXH2 1/20 0.32
▸ USP19 O94966 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31553300 0.87 HRH3 (0.40) SLC34A1MAPTALDH1A1LMNAL3MBTL1
SCHEMBL30747719 0.86 OPRL1 (0.36) —
SCHEMBL30747696 0.85 KMT2A (0.45) SLC34A1LMNA
SCHEMBL30747594 0.84 ADORA2A (0.33) —
SCHEMBL30747567 0.84 MET (0.36) KDM4E
SCHEMBL30747592 0.83 CCR3 (0.43) —
SCHEMBL31553349 0.82 MTOR (0.33) SLC34A1
SCHEMBL30747484 0.82 BRD4 (0.39) SLC34A1MAPTALDH1A1LMNAL3MBTL1
SCHEMBL30747705 0.81 CCR3 (0.45) HTR2C
SCHEMBL30747498 0.81 HRH3 (0.39) SLC34A1ALDH1A1LMNAL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4539938-A1 PYRIDAZINONE-DERIVED COMPOUNDS FOR THE MODULATION OF MYC AND FOR MEDICAL USES Genetic Intelligence, Inc (US) 2025-04-23 — — EP disclosed
CN-119855813-A Pyridazinone-derived compounds for modulating MYC and for medical use 遗传智力公司 2025-04-18 — — CN disclosed
WO-2023245091-A1 PYRIDAZINONE-DERIVED COMPOUNDS FOR THE MODULATION OF MYC AND FOR MEDICAL USES Genetic Intelligence, Inc (US) 2023-12-21 — — WO disclosed
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