Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 7/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26649377 | 1.00 | DHODH (0.54) | DHODHMEN1KMT2AALDH1A1GAA | |
| SCHEMBL26649558 | 0.93 | DHODH (0.48) | DHODHMEN1KMT2AALDH1A1GAA | |
| SCHEMBL30747749 | 0.90 | DHODH (0.47) | DHODHMEN1KMT2AALDH1A1GAA | |
| SCHEMBL26649477 | 0.90 | DHODH (0.47) | DHODHMEN1KMT2AALDH1A1GAA | |
| SCHEMBL26649474 | 0.87 | HDAC8 (0.54) | DHODHHDAC6HDAC8HDAC1HDAC2 | |
| SCHEMBL30747820 | 0.87 | PLA2G2A (0.62) | DHODHMEN1KMT2AALDH1A1PLA2G2A | |
| SCHEMBL26649384 | 0.87 | PLA2G2A (0.62) | DHODHMEN1KMT2AALDH1A1PLA2G2A | |
| Hydrochloric Acid SCHEMBL26649609 | 0.86 | DHODH (0.57) | DHODHMEN1KMT2AALDH1A1GAA | |
| SCHEMBL30747809 | 0.86 | PLA2G2A (0.48) | DHODHMEN1KMT2AALDH1A1PLA2G2A | |
| SCHEMBL26649429 | 0.86 | PLA2G2A (0.48) | DHODHMEN1KMT2AALDH1A1PLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023219456-A1 | QUINOLINE-BASED HISTONE DEACETYLASE INHIBITORY SUBSTANCES, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION INCLUDING SAME AS ACTIVE INGREDIENT | 숙명여자대학교 산학협력단 | 2023-11-16 | — | — | WO | claimed |