Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE9A | O76083 | 12/20 | 0.41 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 5/20 | 0.40 |
| ▸ | PDE8B | O95263 | 2/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | TRAP1 | Q12931 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29174835 | 1.00 | PDE9A (0.41) | PDE9APDE1CPDE10APDE8BHSP90AA1 | |
| SCHEMBL30748221 | 1.00 | PDE9A (0.41) | PDE9APDE1CPDE10APDE8BHSP90AA1 | |
| SCHEMBL23059288 | 0.85 | PDE8B (0.45) | PDE9APDE1CPDE8B | |
| SCHEMBL30748213 | 0.85 | PDE9A (0.37) | PDE9APDE1CPDE8B | |
| SCHEMBL29174802 | 0.85 | PDE9A (0.37) | PDE9APDE1CPDE8B | |
| SCHEMBL30095904 | 0.84 | PDE10A (0.43) | PDE10APDE8BHSP90AA1TRAP1 | |
| SCHEMBL29174904 | 0.84 | PDE10A (0.43) | PDE10APDE8BHSP90AA1TRAP1 | |
| SCHEMBL30095754 | 0.83 | PDE9A (0.39) | PDE9APDE1C | |
| SCHEMBL29174800 | 0.83 | PDE9A (0.39) | PDE9APDE1C | |
| SCHEMBL16981657 | 0.81 | PDE9A (0.44) | PDE9APDE1CHSP90AA1TRAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117529315-A | Imidazole-containing ALK2 kinase inhibitors | 生物水晶制药公司 | 2024-02-06 | — | — | CN | disclosed |