Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 8/20 | 0.68 |
| ▸ | BTK | Q06187 | 1/20 | 0.64 |
| ▸ | ULK1 | O75385 | 1/20 | 0.59 |
| ▸ | ALK | Q9UM73 | 10/20 | 0.56 |
| ▸ | INSR | P06213 | 3/20 | 0.55 |
| ▸ | TTK | P33981 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25001760 | 1.00 | EGFR (0.68) | EGFRBTKULK1ALKINSR | |
| SCHEMBL25001489 | 0.90 | EGFR (0.84) | EGFRBTKULK1ALKTTK | |
| SCHEMBL25001487 | 0.88 | EGFR (0.76) | EGFRBTKULK1ALK | |
| SCHEMBL25001951 | 0.88 | EGFR (0.66) | EGFRBTKULK1ALKINSR | |
| SCHEMBL25002639 | 0.87 | ALK (0.55) | EGFRBTKULK1ALKINSR | |
| SCHEMBL30140980 | 0.87 | EGFR (0.66) | EGFRBTKULK1ALKTTK | |
| SCHEMBL25001794 | 0.87 | EGFR (0.84) | EGFRBTKULK1ALKINSR | |
| SCHEMBL25001761 | 0.86 | EGFR (0.61) | EGFRBTKULK1ALKINSR | |
| SCHEMBL25821864 | 0.86 | EGFR (0.64) | EGFRBTKULK1ALKINSR | |
| SCHEMBL25001766 | 0.85 | ULK1 (0.70) | EGFRBTKULK1ALKINSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112538072-B | Aminopyrimidine EGFR inhibitors | 齐鲁制药有限公司 | 2024-02-06 | — | — | CN | disclosed |