Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 19/20 | 0.48 |
| ▸ | ULK1 | O75385 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25001639 | 1.00 | EGFR (0.48) | EGFRULK1 | |
| SCHEMBL25002978 | 0.89 | EGFR (0.48) | EGFRULK1 | |
| SCHEMBL25001890 | 0.89 | EGFR (0.55) | EGFR | |
| SCHEMBL23441963 | 0.88 | EGFR (0.63) | EGFR | |
| SCHEMBL30748525 | 0.88 | EGFR (0.48) | EGFRULK1 | |
| SCHEMBL25001499 | 0.88 | EGFR (0.48) | EGFRULK1 | |
| SCHEMBL25001612 | 0.87 | EGFR (0.51) | EGFRULK1 | |
| SCHEMBL25001622 | 0.86 | EGFR (0.48) | EGFR | |
| SCHEMBL25002039 | 0.86 | EGFR (0.50) | EGFRULK1 | |
| SCHEMBL25001524 | 0.86 | EGFR (0.47) | EGFRULK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112538072-B | Aminopyrimidine EGFR inhibitors | 齐鲁制药有限公司 | 2024-02-06 | — | — | CN | disclosed |