Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 19/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22026203 | 1.00 | EGFR (0.45) | EGFR | |
| SCHEMBL22025609 | 0.89 | EGFR (0.49) | EGFR | |
| SCHEMBL29757745 | 0.89 | EGFR (0.49) | EGFR | |
| SCHEMBL22025651 | 0.87 | EGFR (0.49) | EGFR | |
| SCHEMBL29747109 | 0.87 | EGFR (0.49) | EGFR | |
| SCHEMBL30018602 | 0.85 | EGFR (0.49) | EGFR | |
| SCHEMBL28609013 | 0.85 | EGFR (0.49) | EGFR | |
| SCHEMBL29877303 | 0.84 | EGFR (0.47) | EGFR | |
| SCHEMBL29258007 | 0.84 | EGFR (0.47) | EGFR | |
| SCHEMBL30018639 | 0.84 | EGFR (0.43) | EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112538072-B | Aminopyrimidine EGFR inhibitors | 齐鲁制药有限公司 | 2024-02-06 | — | — | CN | disclosed |