Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.32 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26650555 | 1.00 | EGFR (0.33) | EGFRBACE1KDM4EMAPTPPARG | |
| SCHEMBL7264434 | 0.77 | NQO2 (0.44) | EGFRBACE1KDM4EMAPTPPARG | |
| SCHEMBL2170889 | 0.77 | BACE1 (0.36) | EGFRBACE1KDM4EMAPTPPARG | |
| SCHEMBL26650884 | 0.74 | EGFR (0.38) | EGFRMAPTRXFP1TDP1 | |
| SCHEMBL31485307 | 0.74 | EGFR (0.38) | EGFRMAPTRXFP1TDP1 | |
| SCHEMBL31373528 | 0.73 | NT5E (0.38) | KDM4E | |
| SCHEMBL26650721 | 0.73 | SOS2 (0.41) | — | |
| SCHEMBL26650704 | 0.73 | NT5E (0.38) | KDM4E | |
| SCHEMBL31485298 | 0.73 | SOS2 (0.41) | — | |
| SCHEMBL31215731 | 0.73 | MEN1 (0.35) | EGFRKDM4EMAPTSMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023217230-A1 | KINESIN KIF18A INHIBITOR AND USE THEREOF | 上海湃隆生物科技有限公司 | 2023-11-16 | — | — | WO | disclosed |