Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PRNP | P04156 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | NQO2 | P16083 | 2/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CLK1 | P49759 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26650884 | 1.00 | EGFR (0.38) | EGFRALDH1A1PRNPMAPTNPSR1 | |
| SCHEMBL7266128 | 0.82 | NQO2 (0.42) | EGFRALDH1A1PRNPMAPTNPSR1 | |
| SCHEMBL2192770 | 0.81 | EGFR (0.37) | EGFRALDH1A1PRNPMAPTNPSR1 | |
| SCHEMBL20563188 | 0.80 | RAF1 (0.36) | MAPTHSP90AA1HSP90AB1CYP1A2KMT2A | |
| SCHEMBL30748588 | 0.74 | EGFR (0.33) | EGFRMAPTRXFP1TDP1 | |
| SCHEMBL26650555 | 0.74 | EGFR (0.33) | EGFRMAPTRXFP1TDP1 | |
| SCHEMBL31403124 | 0.74 | PTGS2 (0.40) | — | |
| SCHEMBL18544257 | 0.72 | MTNR1A (0.47) | KMT2ACLK1MTNR1AMTNR1B | |
| SCHEMBL26650835 | 0.71 | HSP90AA1 (0.35) | EGFRNQO2HSP90AA1HSP90AB1CYP1A2 | |
| SCHEMBL16511925 | 0.71 | MTNR1A (0.44) | CYP1A2KMT2ACLK1MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4524135-A1 | KINESIN KIF18A INHIBITOR AND USE THEREOF | Shanghai Apeiron Therapeutics Company Limited (CN) | 2025-03-19 | — | — | EP | disclosed |