Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | TLR2 | O60603 | 3/20 | 0.37 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.35 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25391589 | 1.00 | KMT2A (0.52) | KMT2AEPHX2LMNASMN1; SMN2CASP3 | |
| SCHEMBL25390706 | 1.00 | KMT2A (0.52) | KMT2AEPHX2LMNASMN1; SMN2CASP3 | |
| SCHEMBL16942065 | 1.00 | KMT2A (0.52) | KMT2AEPHX2LMNASMN1; SMN2CASP3 | |
| SCHEMBL22342591 | 0.92 | KMT2A (0.49) | KMT2AEPHX2LMNASMN1; SMN2CASP3 | |
| SCHEMBL3087950 | 0.89 | KMT2A (0.58) | KMT2AEPHX2CASP3 | |
| SCHEMBL26032361 | 0.87 | KMT2A (0.58) | KMT2AEPHX2LMNASMN1; SMN2CASP3 | |
| SCHEMBL7855942 | 0.85 | KMT2A (0.69) | KMT2AEPHX2CASP3TLR2TLR1 | |
| SCHEMBL31657114 | 0.85 | CASP3 (0.41) | KMT2ACASP3TLR2 | |
| SCHEMBL22279559 | 0.84 | KMT2A (0.59) | KMT2AEPHX2LMNASMN1; SMN2CASP3 | |
| SCHEMBL15146937 | 0.84 | KMT2A (0.59) | KMT2AEPHX2LMNASMN1; SMN2CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025054459-A1 | RNAI OLIGONUCLEOTIDE CONJUGATES | DICERNA PHARMACEUTICALS, INC. (US) | 2025-03-13 | — | — | WO | disclosed |
| CN-117279662-A | Branched linkers for antibody-drug conjugates and methods of use thereof | R.P.谢勒技术有限责任公司 | 2023-12-22 | — | — | CN | disclosed |