SCHEMBL30748889

SCHEMBL30748889

C=Cc1ncc2c(n1)N(c1ccc(OC3CCCCC3)nc1)C(=O)C21CC1

nearest known ligand 0.36

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CCNE1 P24864 6/20 0.36
CDK2 P24941 6/20 0.36
BTK Q06187 2/20 0.35
AR P10275 5/20 0.34
ACACB O00763 2/20 0.34
HRH3 Q9Y5N1 4/20 0.32
CDK1 P06493 1/20 0.32
LCAT P04180 1/20 0.31
KCNH2 Q12809 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30749078 0.91 CCNE1 (0.36) CCNE1CDK2BTKARACACB
SCHEMBL30748806 0.85 AR (0.38) CCNE1CDK2BTKARACACB
SCHEMBL30748958 0.84 AR (0.38) CCNE1CDK2BTKARACACB
SCHEMBL30748908 0.83 ACACB (0.37) CCNE1CDK2BTKARACACB
SCHEMBL30749098 0.82 CCNE1 (0.36) CCNE1CDK2BTKARACACB
SCHEMBL30748803 0.80 CCNE1 (0.39) CCNE1CDK2BTKARACACB
SCHEMBL30748954 0.78 CDK2 (0.37) CCNE1CDK2BTKARACACB
SCHEMBL31691301 0.76 CCNE1 (0.34) CCNE1CDK2BTKARACACB
SCHEMBL30749103 0.74 EGLN1 (0.44) CCNE1CDK2BTK
SCHEMBL31691263 0.72 CCNE1 (0.35) CCNE1CDK2ARHRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250304571-A1 BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF SUZHOU KEEN THERAPEUTICS CO., LTD. (CN) 2025-10-02 US disclosed
EP-4565588-A1 BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF Suzhou Keen Therapeutics Co., Ltd. (CN) 2025-06-11 EP disclosed
WO-2023241620-A1 BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF SUZHOU KEEN THERAPEUTICS CO., LTD. (CN) 2023-12-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250304571-A1 BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF VHL, BRCA1, TERT CCNE1 2310/4885CDK2 680/4885BTK 1727/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.