Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
| ▸ | LPL | P06858 | 5/20 | 0.40 |
| ▸ | LIPG | Q9Y5X9 | 5/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15657536 | 1.00 | KDM4E (0.46) | KDM4EHTTPDE3BPDE3AROCK1 | |
| SCHEMBL14241709 | 0.85 | ROCK1 (0.38) | PDE3BPDE3AROCK1LPLLIPG | |
| SCHEMBL4495894 | 0.82 | ALDH1A1 (0.39) | KDM4EHTTPDE3BPDE3AROCK1 | |
| SCHEMBL25715171 | 0.81 | ALDH1A1 (0.44) | HTTROCK1LPLLIPGALDH1A1 | |
| SCHEMBL27159745 | 0.80 | ALDH1A1 (0.36) | KDM4EHTTROCK1LPLLIPG | |
| SCHEMBL17531637 | 0.80 | ALDH1A1 (0.44) | HTTROCK1LPLLIPGALDH1A1 | |
| Hydrochloric Acid SCHEMBL27204333 | 0.79 | ALDH1A1 (0.35) | KDM4EHTTROCK1LPLLIPG | |
| Hydrochloric Acid SCHEMBL27159838 | 0.79 | ALDH1A1 (0.35) | KDM4EHTTROCK1LPLLIPG | |
| SCHEMBL27009116 | 0.79 | ROCK1 (0.41) | PDE3BPDE3AROCK1LPLLIPG | |
| SCHEMBL13718438 | 0.78 | ALDH1A1 (0.46) | KDM4EHTTPDE3BPDE3AROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4565588-A1 | BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF | Suzhou Keen Therapeutics Co., Ltd. (CN) | 2025-06-11 | — | — | EP | disclosed |
| WO-2023241620-A1 | BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF | SUZHOU KEEN THERAPEUTICS CO., LTD. (CN) | 2023-12-21 | — | — | WO | disclosed |