SCHEMBL30749003

SCHEMBL30749003

O=C1N(c2cnc(N3CC4CC3CO4)nc2)c2nc(Cl)nc(Cl)c2C12CCCC2

nearest known ligand 0.36

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ACACB O00763 2/20 0.36
MAP3K12 Q12852 15/20 0.35
MTOR P42345 2/20 0.33
PIK3CA P42336 2/20 0.33
PIK3R1 P27986 1/20 0.33
MAP3K13 O43283 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30748999 1.00 ACACB (0.36) ACACBMAP3K12MTORPIK3CAPIK3R1
SCHEMBL31691339 0.84 ACACB (0.35) ACACBMAP3K12PIK3CAPIK3R1
SCHEMBL31691410 0.80 MTOR (0.31) MTOR
SCHEMBL31691407 0.79 PIK3CA (0.34) ACACBMAP3K12MTORPIK3CAPIK3R1
SCHEMBL30749044 0.76 ALDH1A1 (0.34)
SCHEMBL31691217 0.75 ACACB (0.33) ACACBMAP3K12PIK3CAPIK3R1
SCHEMBL31627095 0.69
SCHEMBL30748824 0.69 KMT2A (0.37)
SCHEMBL30067817 0.69 PDE10A (0.39) MAP3K12MTORPIK3CA
SCHEMBL30748771 0.69 KMT2A (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4565588-A1 BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF Suzhou Keen Therapeutics Co., Ltd. (CN) 2025-06-11 EP disclosed
WO-2023241620-A1 BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF SUZHOU KEEN THERAPEUTICS CO., LTD. (CN) 2023-12-21 WO disclosed