⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31691432 | 0.81 | KDM5B (0.30) | — | |
| SCHEMBL30748929 | 0.79 | ALOX15 (0.33) | — | |
| SCHEMBL30749096 | 0.76 | — | — | |
| SCHEMBL31691407 | 0.76 | PIK3CA (0.34) | — | |
| SCHEMBL30748947 | 0.75 | PDE8B (0.32) | — | |
| SCHEMBL30748932 | 0.73 | TRPV1 (0.35) | — | |
| SCHEMBL31691422 | 0.71 | CHRM3 (0.37) | — | |
| SCHEMBL30749004 | 0.71 | HDAC6 (0.33) | — | |
| SCHEMBL30748798 | 0.70 | MAPK1 (0.33) | — | |
| SCHEMBL30748916 | 0.69 | HDAC6 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250304571-A1 | BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF | SUZHOU KEEN THERAPEUTICS CO., LTD. (CN) | 2025-10-02 | — | — | US | disclosed |
| EP-4565588-A1 | BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF | Suzhou Keen Therapeutics Co., Ltd. (CN) | 2025-06-11 | — | — | EP | disclosed |
| WO-2023241620-A1 | BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF | SUZHOU KEEN THERAPEUTICS CO., LTD. (CN) | 2023-12-21 | — | — | WO | disclosed |