Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 19/20 | 0.52 |
| ▸ | TPO | P07202 | 17/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27223427 | 1.00 | MPO (0.52) | MPOTPOCYP3A4KCNH2OPRM1 | |
| SCHEMBL27224050 | 0.87 | MPO (0.53) | MPOTPOCYP3A4KCNH2OPRM1 | |
| SCHEMBL30749218 | 0.86 | MPO (0.42) | MPOTPOCYP3A4KCNH2 | |
| SCHEMBL27223539 | 0.83 | MPO (0.47) | MPOTPOCYP3A4KCNH2 | |
| SCHEMBL30749243 | 0.78 | MPO (0.43) | MPOTPOKCNH2OPRM1 | |
| SCHEMBL1536647 | 0.75 | MPO (0.52) | MPOTPOCYP3A4KCNH2OPRM1 | |
| SCHEMBL1536641 | 0.74 | MPO (0.54) | MPOTPOCYP3A4KCNH2OPRM1 | |
| SCHEMBL30749341 | 0.73 | MPO (0.40) | MPOTPOCYP3A4KCNH2 | |
| SCHEMBL27224142 | 0.72 | MPO (0.49) | MPOTPOCYP3A4KCNH2 | |
| SCHEMBL30749175 | 0.72 | MPO (0.52) | MPOTPOCYP3A4KCNH2OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4573096-A1 | INHIBITORS OF MYELOPEROXIDASE | Astrazeneca AB (SE) | 2025-06-25 | — | — | EP | claimed |
| WO-2024038131-A1 | INHIBITORS OF MYELOPEROXIDASE | ASTRAZENECA AB (SE) | 2024-02-22 | — | — | WO | claimed |
| EP-4573096-A1 | INHIBITORS OF MYELOPEROXIDASE | Astrazeneca AB (SE) | 2025-06-25 | — | — | EP | disclosed |
| WO-2024038131-A1 | INHIBITORS OF MYELOPEROXIDASE | ASTRAZENECA AB (SE) | 2024-02-22 | — | — | WO | disclosed |