Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 7/20 | 0.53 |
| ▸ | BACE1 | P56817 | 1/20 | 0.47 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 5/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PDE5A | O76074 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31556681 | 1.00 | NR1H2 (0.53) | NR1H2BACE1UCHL1NR1H3USP2 | |
| SCHEMBL30749323 | 0.88 | NR1H2 (0.45) | NR1H2BACE1UCHL1NR1H3USP2 | |
| SCHEMBL30899777 | 0.84 | NR1H2 (0.39) | NR1H2BACE1NR1H3USP2SMN1; SMN2 | |
| SCHEMBL29747858 | 0.84 | NR1H2 (0.41) | NR1H2BACE1NR1H3USP2SMN1; SMN2 | |
| SCHEMBL31556713 | 0.84 | NR1H2 (0.39) | NR1H2BACE1NR1H3USP2SMN1; SMN2 | |
| SCHEMBL14829637 | 0.83 | NR1H2 (0.49) | NR1H2BACE1NR1H3USP2SMN1; SMN2 | |
| SCHEMBL3312132 | 0.83 | NR1H2 (0.57) | NR1H2UCHL1TSHRMEN1ALDH1A1 | |
| SCHEMBL2325712 | 0.83 | NR1H2 (0.57) | NR1H2UCHL1TSHRMEN1ALDH1A1 | |
| SCHEMBL13749174 | 0.83 | NR1H2 (0.49) | NR1H2BACE1NR1H3USP2SMN1; SMN2 | |
| SCHEMBL3313724 | 0.83 | NR1H2 (0.57) | NR1H2UCHL1TSHRMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4573096-A1 | INHIBITORS OF MYELOPEROXIDASE | Astrazeneca AB (SE) | 2025-06-25 | — | — | EP | disclosed |
| CN-119894896-A | Inhibitors of green peroxidase | 阿斯利康(瑞典)有限公司 | 2025-04-25 | — | — | CN | disclosed |
| WO-2024038131-A1 | INHIBITORS OF MYELOPEROXIDASE | ASTRAZENECA AB (SE) | 2024-02-22 | — | — | WO | disclosed |