Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 6/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 4/20 | 0.35 |
| ▸ | PDE5A | O76074 | 1/20 | 0.35 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.35 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
| ▸ | KLK7 | P49862 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31556713 | 0.90 | NR1H2 (0.39) | NR1H2BACE1TSHRMEN1ALDH1A1 | |
| SCHEMBL30899777 | 0.90 | NR1H2 (0.39) | NR1H2BACE1TSHRMEN1ALDH1A1 | |
| SCHEMBL31556681 | 0.88 | NR1H2 (0.53) | NR1H2BACE1TSHRMEN1ALDH1A1 | |
| SCHEMBL30749206 | 0.88 | NR1H2 (0.53) | NR1H2BACE1TSHRMEN1ALDH1A1 | |
| SCHEMBL27223597 | 0.83 | BACE1 (0.42) | BACE1TSHRMEN1ALDH1A1LMNA | |
| SCHEMBL27231896 | 0.83 | BACE1 (0.42) | BACE1TSHRMEN1ALDH1A1LMNA | |
| SCHEMBL27224160 | 0.81 | BACE1 (0.57) | BACE1TSHRMEN1ALDH1A1LMNA | |
| SCHEMBL27224210 | 0.81 | BACE1 (0.57) | BACE1TSHRMEN1ALDH1A1LMNA | |
| SCHEMBL30749213 | 0.77 | TSHR (0.42) | TSHRMEN1ALDH1A1LMNAKMT2A | |
| SCHEMBL27224118 | 0.77 | TSHR (0.42) | TSHRMEN1ALDH1A1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4573096-A1 | INHIBITORS OF MYELOPEROXIDASE | Astrazeneca AB (SE) | 2025-06-25 | — | — | EP | disclosed |
| WO-2024038131-A1 | INHIBITORS OF MYELOPEROXIDASE | ASTRAZENECA AB (SE) | 2024-02-22 | — | — | WO | disclosed |