Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CCNC | P24863 | 1/20 | 0.39 |
| ▸ | CDK8 | P49336 | 1/20 | 0.39 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27224118 | 1.00 | TSHR (0.42) | TSHRMEN1KMT2ALMNAMAPT | |
| SCHEMBL27224064 | 0.86 | ALDH1A1 (0.51) | TSHRMEN1KMT2ALMNAMAPT | |
| SCHEMBL30749329 | 0.86 | ALDH1A1 (0.51) | TSHRMEN1KMT2ALMNAMAPT | |
| SCHEMBL31556713 | 0.85 | NR1H2 (0.39) | TSHRMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL30899777 | 0.85 | NR1H2 (0.39) | TSHRMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL30749316 | 0.85 | ALDH1A1 (0.48) | TSHRMEN1KMT2ALMNAMAPT | |
| SCHEMBL27224030 | 0.85 | ALDH1A1 (0.48) | TSHRMEN1KMT2ALMNAMAPT | |
| SCHEMBL31556715 | 0.84 | ALDH1A1 (0.47) | TSHRMEN1KMT2ALMNAMAPT | |
| SCHEMBL30749292 | 0.84 | ALDH1A1 (0.47) | TSHRMEN1KMT2ALMNAMAPT | |
| SCHEMBL27224046 | 0.83 | CCNC (0.41) | MEN1KMT2ALMNAALDH1A1CCNC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4573096-A1 | INHIBITORS OF MYELOPEROXIDASE | Astrazeneca AB (SE) | 2025-06-25 | — | — | EP | disclosed |
| WO-2024038131-A1 | INHIBITORS OF MYELOPEROXIDASE | ASTRAZENECA AB (SE) | 2024-02-22 | — | — | WO | disclosed |