Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 1/20 | 0.37 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.37 |
| ▸ | NSD2 | O96028 | 1/20 | 0.30 |
| ▸ | CASP6 | P55212 | 1/20 | 0.30 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.30 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8712013 | 1.00 | TRIM24 (0.37) | TRIM24TRIM33NSD2CASP6CYP11B1 | |
| SCHEMBL9542666 | 0.77 | NPC1 (0.39) | — | |
| SCHEMBL170059 | 0.77 | NAPRT (0.36) | — | |
| SCHEMBL28546297 | 0.74 | TRIM24 (0.35) | TRIM24TRIM33 | |
| SCHEMBL28036738 | 0.74 | PDK2 (0.46) | TRIM24TRIM33CYP11B1CYP11B2 | |
| SCHEMBL17796068 | 0.73 | NSD2 (0.36) | NSD2CASP6 | |
| SCHEMBL24417412 | 0.73 | CYP11B1 (0.35) | CYP11B1CYP11B2 | |
| SCHEMBL21505570 | 0.73 | TRIM24 (0.34) | TRIM24TRIM33 | |
| SCHEMBL26123737 | 0.73 | GAA (0.33) | NSD2CASP6 | |
| SCHEMBL5347558 | 0.72 | DRD2 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4573096-A1 | INHIBITORS OF MYELOPEROXIDASE | Astrazeneca AB (SE) | 2025-06-25 | — | — | EP | disclosed |
| CN-119894896-A | Inhibitors of green peroxidase | 阿斯利康(瑞典)有限公司 | 2025-04-25 | — | — | CN | disclosed |
| WO-2024038131-A1 | INHIBITORS OF MYELOPEROXIDASE | ASTRAZENECA AB (SE) | 2024-02-22 | — | — | WO | disclosed |