Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 2/20 | 0.46 |
| ▸ | JAK1 | P23458 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.39 |
| ▸ | HPGDS | O60760 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.37 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27224082 | 1.00 | JAK2 (0.46) | JAK2JAK1MEN1KMT2AKDM4E | |
| SCHEMBL30749339 | 0.91 | JAK2 (0.43) | JAK2JAK1MEN1KMT2AKDM4E | |
| SCHEMBL27223438 | 0.91 | JAK2 (0.43) | JAK2JAK1MEN1KMT2AKDM4E | |
| SCHEMBL27224143 | 0.89 | TSHR (0.38) | JAK2JAK1MEN1KMT2AKDM4E | |
| SCHEMBL27223619 | 0.85 | IDO1 (0.37) | JAK2JAK1MEN1KMT2AKDM4E | |
| SCHEMBL30749256 | 0.85 | IDO1 (0.37) | JAK2JAK1MEN1KMT2AKDM4E | |
| SCHEMBL27223567 | 0.85 | ATM (0.38) | JAK2JAK1MEN1KMT2AMAPT | |
| SCHEMBL27223426 | 0.84 | KMT2A (0.47) | MEN1KMT2AKDM4EALDH1A1GLA | |
| SCHEMBL30749239 | 0.84 | KMT2A (0.47) | MEN1KMT2AKDM4EALDH1A1GLA | |
| SCHEMBL30749254 | 0.84 | KMT2A (0.46) | MEN1KMT2AKDM4EALDH1A1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4573096-A1 | INHIBITORS OF MYELOPEROXIDASE | Astrazeneca AB (SE) | 2025-06-25 | — | — | EP | disclosed |
| WO-2024038131-A1 | INHIBITORS OF MYELOPEROXIDASE | ASTRAZENECA AB (SE) | 2024-02-22 | — | — | WO | disclosed |