Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27224042 | 1.00 | KMT2A (0.46) | KMT2AMEN1ALDH1A1LMNATP53 | |
| SCHEMBL27223426 | 0.99 | KMT2A (0.47) | KMT2AMEN1ALDH1A1LMNATP53 | |
| SCHEMBL30749239 | 0.99 | KMT2A (0.47) | KMT2AMEN1ALDH1A1LMNATP53 | |
| Hydrochloric Acid SCHEMBL30749296 | 0.93 | KMT2A (0.41) | KMT2AMEN1ALDH1A1LMNATP53 | |
| SCHEMBL27224168 | 0.90 | ALOX15 (0.39) | KMT2AMEN1ALDH1A1KDM4EALOX15 | |
| SCHEMBL27224058 | 0.89 | ALDH1A1 (0.39) | KMT2AMEN1ALDH1A1KDM4EALOX15 | |
| SCHEMBL30749308 | 0.88 | ALDH1A1 (0.45) | KMT2AMEN1ALDH1A1LMNATP53 | |
| SCHEMBL27224054 | 0.88 | ALDH1A1 (0.45) | KMT2AMEN1ALDH1A1LMNATP53 | |
| SCHEMBL30749240 | 0.87 | MEN1 (0.40) | KMT2AMEN1ALDH1A1LMNATP53 | |
| SCHEMBL31556733 | 0.87 | MEN1 (0.40) | KMT2AMEN1ALDH1A1LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4573096-A1 | INHIBITORS OF MYELOPEROXIDASE | Astrazeneca AB (SE) | 2025-06-25 | — | — | EP | disclosed |
| CN-119894896-A | Inhibitors of green peroxidase | 阿斯利康(瑞典)有限公司 | 2025-04-25 | — | — | CN | disclosed |
| WO-2024038131-A1 | INHIBITORS OF MYELOPEROXIDASE | ASTRAZENECA AB (SE) | 2024-02-22 | — | — | WO | disclosed |