Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 16/20 | 0.73 |
| ▸ | TPO | P07202 | 10/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | PNP | P00491 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 2/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27224026 | 1.00 | MPO (0.73) | MPOTPOCYP3A4KCNH2PNP | |
| SCHEMBL27223469 | 0.84 | MPO (1.00) | MPOTPOCYP3A4KCNH2 | |
| SCHEMBL27223627 | 0.84 | MPO (1.00) | MPOTPOCYP3A4KCNH2 | |
| SCHEMBL30749233 | 0.84 | MPO (1.00) | MPOTPOCYP3A4KCNH2 | |
| SCHEMBL27223420 | 0.84 | MPO (1.00) | MPOTPOCYP3A4KCNH2 | |
| SCHEMBL30749179 | 0.84 | MPO (1.00) | MPOTPOCYP3A4KCNH2 | |
| SCHEMBL30749184 | 0.84 | MPO (1.00) | MPOTPOCYP3A4KCNH2 | |
| SCHEMBL30749197 | 0.84 | MPO (1.00) | MPOTPOCYP3A4KCNH2 | |
| SCHEMBL30749224 | 0.80 | MPO (1.00) | MPOTPOCYP3A4KCNH2PNP | |
| SCHEMBL30749189 | 0.80 | MPO (1.00) | MPOTPOCYP3A4KCNH2PNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4573096-A1 | INHIBITORS OF MYELOPEROXIDASE | Astrazeneca AB (SE) | 2025-06-25 | — | — | EP | disclosed |
| WO-2024038131-A1 | INHIBITORS OF MYELOPEROXIDASE | ASTRAZENECA AB (SE) | 2024-02-22 | — | — | WO | disclosed |