Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 19/20 | 0.45 |
| ▸ | TPO | P07202 | 18/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30749243 | 0.90 | MPO (0.43) | MPOTPOKCNH2OPRM1 | |
| SCHEMBL27224142 | 0.86 | MPO (0.49) | MPOTPOKCNH2CYP3A4 | |
| SCHEMBL28896649 | 0.77 | MPO (0.53) | MPOTPOKCNH2OPRM1CYP3A4 | |
| SCHEMBL27224050 | 0.76 | MPO (0.53) | MPOTPOKCNH2OPRM1CYP3A4 | |
| SCHEMBL27223539 | 0.76 | MPO (0.47) | MPOTPOKCNH2CYP3A4 | |
| SCHEMBL29211238 | 0.76 | MPO (0.56) | MPOTPOKCNH2CYP3A4 | |
| SCHEMBL30749377 | 0.74 | MPO (0.44) | MPOTPOKCNH2OPRM1CYP3A4 | |
| SCHEMBL29211240 | 0.73 | MPO (0.52) | MPOTPOKCNH2OPRM1CYP3A4 | |
| SCHEMBL22918218 | 0.71 | AKT1 (0.40) | — | |
| SCHEMBL30601263 | 0.70 | MPO (0.67) | MPOTPOKCNH2OPRM1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4573096-A1 | INHIBITORS OF MYELOPEROXIDASE | Astrazeneca AB (SE) | 2025-06-25 | — | — | EP | disclosed |
| WO-2024038131-A1 | INHIBITORS OF MYELOPEROXIDASE | ASTRAZENECA AB (SE) | 2024-02-22 | — | — | WO | disclosed |