Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | GLS | O94925 | 1/20 | 0.35 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 4/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.34 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27223550 | 1.00 | ALDH1A1 (0.35) | ALDH1A1LMNANPSR1ATMGLS | |
| SCHEMBL27223486 | 0.92 | ALDH1A1 (0.36) | ALDH1A1LMNANPSR1KDM4EPKM | |
| SCHEMBL27224036 | 0.87 | ATM (0.35) | ALDH1A1LMNANPSR1ATMDDB1 | |
| SCHEMBL30749223 | 0.85 | KDM4E (0.42) | ALDH1A1LMNANPSR1ATMKDM4E | |
| SCHEMBL27224069 | 0.85 | KDM4E (0.42) | ALDH1A1LMNANPSR1ATMKDM4E | |
| SCHEMBL30749291 | 0.83 | USP30 (0.41) | ALDH1A1NPSR1ATMKDM4EPKM | |
| SCHEMBL27223546 | 0.83 | USP30 (0.41) | ALDH1A1NPSR1ATMKDM4EPKM | |
| SCHEMBL27224149 | 0.82 | ATM (0.36) | ALDH1A1LMNANPSR1ATMKDM4E | |
| SCHEMBL30749259 | 0.81 | MEN1 (0.40) | ALDH1A1LMNANPSR1ATMKDM4E | |
| SCHEMBL27223613 | 0.81 | MEN1 (0.40) | ALDH1A1LMNANPSR1ATMKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4573096-A1 | INHIBITORS OF MYELOPEROXIDASE | Astrazeneca AB (SE) | 2025-06-25 | — | — | EP | disclosed |
| WO-2024038131-A1 | INHIBITORS OF MYELOPEROXIDASE | ASTRAZENECA AB (SE) | 2024-02-22 | — | — | WO | disclosed |