SCHEMBL30749332

SCHEMBL30749332

CC(C)(C)OC(=O)N1CC(C(F)(F)F)CCC1c1ccccc1Cn1c(=S)[nH]c(=O)c2[nH]ccc21

nearest known ligand 0.58

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ MPO P05164 20/20 0.58
▸ TPO P07202 14/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27223418 1.00 MPO (0.58) MPOTPO
SCHEMBL30749317 0.87 MPO (0.59) MPOTPO
SCHEMBL27223477 0.87 MPO (0.59) MPOTPO
SCHEMBL30749298 0.87 MPO (0.58) MPOTPO
SCHEMBL27224127 0.87 MPO (0.58) MPOTPO
SCHEMBL27224137 0.82 MPO (0.50) MPOTPO
SCHEMBL30749356 0.82 MPO (0.50) MPOTPO
SCHEMBL27223618 0.82 MPO (0.57) MPOTPO
SCHEMBL30749207 0.82 MPO (0.57) MPOTPO
SCHEMBL30749277 0.81 MPO (0.56) MPOTPO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4573096-A1 INHIBITORS OF MYELOPEROXIDASE Astrazeneca AB (SE) 2025-06-25 — — EP disclosed
WO-2024038131-A1 INHIBITORS OF MYELOPEROXIDASE ASTRAZENECA AB (SE) 2024-02-22 — — WO disclosed
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