Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 2/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.37 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.37 |
| ▸ | AHCY | P23526 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | F12 | P00748 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | F7 | P08709 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30749234 | 0.93 | ALDH1A1 (0.54) | ALDH1A1TSHRLMNAMEN1KMT2A | |
| SCHEMBL27224081 | 0.93 | ALDH1A1 (0.54) | ALDH1A1TSHRLMNAMEN1KMT2A | |
| SCHEMBL27224030 | 0.92 | ALDH1A1 (0.48) | ALDH1A1TSHRLMNAMEN1KMT2A | |
| SCHEMBL30749316 | 0.92 | ALDH1A1 (0.48) | ALDH1A1TSHRLMNAMEN1KMT2A | |
| SCHEMBL31556715 | 0.91 | ALDH1A1 (0.47) | ALDH1A1TSHRLMNAMEN1KMT2A | |
| SCHEMBL30749292 | 0.91 | ALDH1A1 (0.47) | ALDH1A1TSHRLMNAMEN1KMT2A | |
| SCHEMBL30899767 | 0.90 | ALDH1A1 (0.58) | ALDH1A1TSHRLMNAMEN1KMT2A | |
| SCHEMBL27223962 | 0.90 | ALDH1A1 (0.58) | ALDH1A1TSHRLMNAMEN1KMT2A | |
| SCHEMBL30749329 | 0.89 | ALDH1A1 (0.51) | ALDH1A1TSHRLMNAMEN1KMT2A | |
| SCHEMBL27224064 | 0.89 | ALDH1A1 (0.51) | ALDH1A1TSHRLMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4573096-A1 | INHIBITORS OF MYELOPEROXIDASE | Astrazeneca AB (SE) | 2025-06-25 | — | — | EP | disclosed |
| WO-2024038131-A1 | INHIBITORS OF MYELOPEROXIDASE | ASTRAZENECA AB (SE) | 2024-02-22 | — | — | WO | disclosed |