Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 6/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.39 |
| ▸ | LATS1 | O95835 | 4/20 | 0.36 |
| ▸ | LATS2 | Q9NRM7 | 1/20 | 0.36 |
| ▸ | UBE2N | P61088 | 1/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.35 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.35 |
| ▸ | KDM5A | P29375 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.35 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.34 |
| ▸ | HPGDS | O60760 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL30391689 | 0.89 | EGFR (0.43) | EGFRL3MBTL1LATS1LATS2UBE2N | |
| Trifluoroacetic Acid SCHEMBL29977443 | 0.89 | EGFR (0.43) | EGFRL3MBTL1LATS1LATS2UBE2N | |
| SCHEMBL88606 | 0.82 | EGFR (0.58) | EGFRKDM4C | |
| SCHEMBL29409356 | 0.82 | EGFR (0.58) | EGFRKDM4C | |
| Quinazoline SCHEMBL27562308 | 0.82 | EGFR (0.67) | EGFRL3MBTL1UBE2NIMPDH2 | |
| Trifluoroacetic Acid SCHEMBL30343227 | 0.81 | L3MBTL1 (0.42) | L3MBTL1LATS1LATS2UBE2NCDK5 | |
| Hydrochloric Acid SCHEMBL30749407 | 0.80 | EGFR (0.56) | EGFRKDM4C | |
| Hydrochloric Acid SCHEMBL30749417 | 0.80 | EGFR (0.56) | EGFRKDM4C | |
| Formic Acid SCHEMBL30064211 | 0.80 | EGFR (0.47) | EGFRIMPDH2HIPK2 | |
| Trifluoroacetic Acid SCHEMBL28162941 | 0.79 | EGFR (0.35) | EGFRL3MBTL1UBE2NCDK5CDK5R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117425654-A | 2, 8-diazaspiro [4.5] decane compounds | 基因泰克公司 | 2024-01-19 | — | — | CN | disclosed |