Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | LATS1 | O95835 | 7/20 | 0.33 |
| ▸ | LATS2 | Q9NRM7 | 6/20 | 0.33 |
| ▸ | PDE5A | O76074 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30749395 | 0.99 | PDE5A (0.35) | NR1I2LATS1LATS2PDE5AFAAH | |
| SCHEMBL38660096 | 0.85 | GPR84 (0.34) | LATS1LATS2PDE5AFAAHTDP1 | |
| SCHEMBL30402892 | 0.83 | TLR8 (0.41) | NR1I2SMN1; SMN2 | |
| SCHEMBL30543203 | 0.83 | TLR8 (0.41) | NR1I2SMN1; SMN2 | |
| SCHEMBL30749411 | 0.82 | NR1I2 (0.36) | NR1I2LATS1LATS2FAAHTDP1 | |
| SCHEMBL30746985 | 0.82 | GPBAR1 (0.41) | NR1I2L3MBTL1KDM4ESMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL30543224 | 0.81 | GPBAR1 (0.40) | NR1I2SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11061109 | 0.80 | PDE5A (0.35) | NR1I2LATS1LATS2PDE5AFAAH | |
| SCHEMBL8218133 | 0.77 | TLR8 (0.38) | L3MBTL1KDM4ESMN1; SMN2 | |
| SCHEMBL30749402 | 0.76 | NR1I2 (0.32) | NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117425654-A | 2, 8-diazaspiro [4.5] decane compounds | 基因泰克公司 | 2024-01-19 | — | — | CN | disclosed |