SCHEMBL30749457

SCHEMBL30749457

Cc1cc(C(c2ccc(N)c(C)c2)c2ccc(N)c(C)c2)ccc1N

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 8/20 0.54
TDP1 Q9NUW8 7/20 0.54
ALDH1A1 P00352 6/20 0.54
TSHR P16473 3/20 0.54
S100B P04271 1/20 0.42
MAPK1 P28482 2/20 0.42
SKP2 Q13309 1/20 0.41
THRB P10828 3/20 0.39
ALOX15 P16050 3/20 0.39
HIF1A Q16665 3/20 0.39
RECQL P46063 1/20 0.39
TP53 P04637 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
ESR1 P03372 2/20 0.37
AR P10275 1/20 0.37
ESR2 Q92731 1/20 0.37
CASP1 P29466 1/20 0.37
RAD52 P43351 2/20 0.36
KDM4E B2RXH2 1/20 0.36
MAPT P10636 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5166514 1.00 CYP3A4 (0.54) CYP3A4TDP1ALDH1A1TSHRS100B
SCHEMBL13070208 0.91 ALDH1A1 (0.46) CYP3A4TDP1ALDH1A1TSHRS100B
SCHEMBL109819 0.91 CYP3A4 (0.46) CYP3A4TDP1ALDH1A1TSHRS100B
SCHEMBL30602820 0.91 CYP3A4 (0.46) CYP3A4TDP1ALDH1A1TSHRS100B
SCHEMBL31409207 0.91 ALDH1A1 (0.46) CYP3A4TDP1ALDH1A1TSHRS100B
SCHEMBL743578 0.89 CYP3A4 (0.45) CYP3A4TDP1ALDH1A1TSHRS100B
SCHEMBL29278568 0.89 CYP3A4 (0.45) CYP3A4TDP1ALDH1A1TSHRS100B
SCHEMBL22044374 0.86 ALDH1A1 (0.52) CYP3A4TDP1ALDH1A1TSHRS100B
SCHEMBL22044383 0.86 ALDH1A1 (0.48) CYP3A4TDP1ALDH1A1TSHRS100B
SCHEMBL1596340 0.85 CYP3A4 (0.54) CYP3A4TDP1ALDH1A1TSHRS100B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4321547-A1 CROSSLINKABLE SYSTEMS Prefere Resins Holding GmbH (DE) 2024-02-14 EP claimed
EP-4321547-A1 CROSSLINKABLE SYSTEMS Prefere Resins Holding GmbH (DE) 2024-02-14 EP disclosed