Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.46 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.46 |
| ▸ | ECE1 | P42892 | 2/20 | 0.46 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.39 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.38 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.38 |
| ▸ | ITGAL | P20701 | 1/20 | 0.38 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30288007 | 0.94 | PDCD1LG2 (0.49) | PDCD1LG2CD274ECE1ACEPTGS1 | |
| SCHEMBL30287994 | 0.91 | PDCD1LG2 (0.47) | PDCD1LG2CD274ECE1ACEPTGS1 | |
| SCHEMBL6810737 | 0.91 | ECE1 (0.48) | PDCD1LG2CD274ECE1ACEPTGS1 | |
| SCHEMBL30581568 | 0.91 | ECE1 (0.48) | PDCD1LG2CD274ECE1ACEPTGS1 | |
| SCHEMBL6810742 | 0.91 | ECE1 (0.48) | PDCD1LG2CD274ECE1ACEPTGS1 | |
| SCHEMBL29723024 | 0.91 | PDCD1LG2 (0.53) | PDCD1LG2CD274ECE1ITGB2ICAM1 | |
| SCHEMBL30206430 | 0.91 | ECE1 (0.53) | PDCD1LG2CD274ECE1ITGB2ICAM1 | |
| SCHEMBL29386102 | 0.91 | ECE1 (0.53) | PDCD1LG2CD274ECE1ITGB2ICAM1 | |
| SCHEMBL6809859 | 0.89 | ECE1 (0.47) | PDCD1LG2CD274ECE1ACEPTGS1 | |
| SCHEMBL6809855 | 0.89 | ECE1 (0.47) | PDCD1LG2CD274ECE1ACEPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117355337-A | Protein-macromolecule conjugates and methods of use thereof | 奥迪曼药业科技有限公司 | 2024-01-05 | — | — | CN | disclosed |