Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 2/20 | 0.47 |
| ▸ | ACE | P12821 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.40 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.40 |
| ▸ | MME | P08473 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | THPO | P40225 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.38 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.38 |
| ▸ | ITGAL | P20701 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6809859 | 1.00 | ECE1 (0.47) | ECE1ACEPTGS1GSTK1MME | |
| SCHEMBL6810742 | 0.98 | ECE1 (0.48) | ECE1ACEPTGS1GSTK1MME | |
| SCHEMBL6810737 | 0.98 | ECE1 (0.48) | ECE1ACEPTGS1GSTK1MME | |
| SCHEMBL30288037 | 0.95 | ACE (0.49) | ECE1ACEPTGS1GSTK1MME | |
| SCHEMBL30287995 | 0.95 | ACE (0.49) | ECE1ACEPTGS1GSTK1MME | |
| SCHEMBL16770226 | 0.94 | ACE (0.50) | ECE1ACEPTGS1GSTK1MME | |
| SCHEMBL10308197 | 0.94 | ACE (0.50) | ECE1ACEPTGS1GSTK1MME | |
| SCHEMBL30390254 | 0.94 | ACE (0.50) | ECE1ACEPTGS1GSTK1MME | |
| SCHEMBL30581568 | 0.92 | ECE1 (0.48) | ECE1ACEPTGS1GSTK1MME | |
| SCHEMBL7148009 | 0.92 | ECE1 (0.53) | ECE1PDCD1LG2CD274ITGB2ICAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040018983-A1 | Antifungal compositions | ACHILLION PHARMACEUTICALS, INC. | 2004-01-29 | — | — | US | claimed |
| WO-2003055448-A2 | ANTIFUNGAL COMPOSITIONS | ACHILLION PHARMACEUTICALS, INC. (US) | 2003-07-10 | — | — | WO | claimed |
| US-20040018983-A1 | Antifungal compositions | ACHILLION PHARMACEUTICALS, INC. | 2004-01-29 | — | — | US | disclosed |
| WO-2003055448-A2 | ANTIFUNGAL COMPOSITIONS | ACHILLION PHARMACEUTICALS, INC. (US) | 2003-07-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040018983-A1 | Antifungal compositions | CNBP, ERG28, AEBP2 | ECE1 3354/4885ACE 3680/4885PTGS1 4155/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.