Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.41 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20133352 | 0.93 | HPGD (0.45) | GPR119HPGDRECQLEPHX1PRMT5 | |
| SCHEMBL30750499 | 0.93 | HPGD (0.45) | GPR119HPGDRECQLEPHX1PRMT5 | |
| SCHEMBL16302472 | 0.92 | HPGD (0.46) | GPR119HPGDRECQLEPHX1PRMT5 | |
| SCHEMBL21458682 | 0.92 | HPGD (0.46) | GPR119HPGDRECQLEPHX1PRMT5 | |
| SCHEMBL21458709 | 0.92 | HPGD (0.46) | GPR119HPGDRECQLEPHX1PRMT5 | |
| SCHEMBL30869902 | 0.92 | HPGD (0.46) | GPR119HPGDRECQLEPHX1PRMT5 | |
| SCHEMBL13096783 | 0.91 | HPGD (0.47) | GPR119HPGDRECQLEPHX1PRMT5 | |
| SCHEMBL4219721 | 0.89 | HPGD (0.48) | GPR119HPGDRECQLEPHX1PRMT5 | |
| SCHEMBL1576027 | 0.89 | HPGD (0.50) | GPR119HPGDRECQLEPHX1PRMT5 | |
| SCHEMBL30750642 | 0.88 | GPR119 (0.43) | GPR119HPGDRECQLEPHX1PRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024054954-A1 | HETEROBIFUNCTIONAL COMPOUNDS AND METHODS OF TREATING DISEASE | HALDA THERAPEUTICS OPCO, INC. (US) | 2024-03-14 | — | — | WO | disclosed |