Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | LOXL2 | Q9Y4K0 | 3/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | MET | P08581 | 1/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31457066 | 0.90 | LOXL2 (0.32) | LOXL2MAOAKCNH2AOC3 | |
| Trifluoroacetic Acid SCHEMBL31457063 | 0.83 | LOXL2 (0.44) | MEN1NPC1RAB9AKMT2ALOXL2 | |
| Trifluoroacetic Acid SCHEMBL30751409 | 0.82 | MAPKAPK2 (0.40) | MEN1NPC1RAB9AKMT2ALOXL2 | |
| Trifluoroacetic Acid SCHEMBL30751458 | 0.82 | MEN1 (0.35) | MEN1NPC1RAB9AKMT2ALOXL2 | |
| Trifluoroacetic Acid SCHEMBL31456965 | 0.82 | LOXL2 (0.35) | MEN1NPC1RAB9AKMT2ALOXL2 | |
| Trifluoroacetic Acid SCHEMBL31456996 | 0.80 | MEN1 (0.34) | MEN1NPC1RAB9AKMT2ALOXL2 | |
| Trifluoroacetic Acid SCHEMBL31456999 | 0.80 | MAPK1 (0.38) | MEN1NPC1RAB9AKMT2ALOXL2 | |
| Trifluoroacetic Acid SCHEMBL31457008 | 0.79 | CREBBP (0.42) | MEN1NPC1RAB9AKMT2APTGDR2 | |
| Trifluoroacetic Acid SCHEMBL30751426 | 0.79 | FFAR4 (0.39) | MEN1NPC1RAB9AKMT2ALOXL2 | |
| Trifluoroacetic Acid SCHEMBL31457026 | 0.78 | LOXL2 (0.35) | LOXL2GRIN2BMETMAOAKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4567035-A1 | NOVEL COMPOUND AS HYPOXIA-INDUCIBLE FACTOR 1(HIF-1) INHIBITOR OR VASCULAR ENDOTHELIAL GROWTH FACTOR (VEGF) INHIBITOR, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | Nextgen Bioscience Co., Ltd. (KR) | 2025-06-11 | — | — | EP | disclosed |
| CN-119654324-A | Novel compounds as hypoxia inducible factor 1 (HIF-1) inhibitors or Vascular Endothelial Growth Factor (VEGF) inhibitors and pharmaceutical compositions comprising the same | 株式会社次代生物科学 | 2025-03-18 | — | — | CN | disclosed |
| WO-2024030000-A1 | NOVEL COMPOUND AS HYPOXIA-INDUCIBLE FACTOR 1(HIF-1) INHIBITOR OR VASCULAR ENDOTHELIAL GROWTH FACTOR (VEGF) INHIBITOR, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | 주식회사 넥스트젠바이오사이언스 | 2024-02-08 | — | — | WO | disclosed |