Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.57 |
| ▸ | ABL1 | P00519 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | PORCN | Q9H237 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.45 |
| ▸ | BCL2 | P10415 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1439714 | 1.00 | NAMPT (0.57) | NAMPTABL1CYP1A2HTR2AHTR2C | |
| SCHEMBL6164499 | 0.83 | NAMPT (0.67) | NAMPTCYP17A1RAB9APORCNBCL2 | |
| SCHEMBL6756707 | 0.81 | NAMPT (0.60) | NAMPTABL1CYP1A2HTR2AHTR2C | |
| SCHEMBL31721184 | 0.80 | NAMPT (0.54) | NAMPTCYP17A1RAB9AMEN1KMT2A | |
| SCHEMBL23265149 | 0.79 | ABL1 (0.75) | ABL1PDGFRBBCRPDGFRA | |
| SCHEMBL29873323 | 0.79 | ABL1 (0.75) | ABL1PDGFRBBCRPDGFRA | |
| SCHEMBL31721315 | 0.79 | ABL1 (0.49) | NAMPTABL1PDGFRBBCRPDGFRA | |
| SCHEMBL26949494 | 0.79 | FAAH (0.50) | ABL1CYP1A2HTR2AHTR2CHTR2B | |
| SCHEMBL4832910 | 0.79 | GAA (0.64) | ABL1RAB9AMEN1KMT2ANPC1 | |
| SCHEMBL349933 | 0.79 | NAMPT (0.80) | NAMPTCYP1A2RAB9ALMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112300172-B | Bruton tyrosine kinase inhibitors | 比奥根MA公司 | 2024-01-16 | — | — | CN | disclosed |