⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31438307 | 0.81 | CSNK2A2 (0.31) | — | |
| SCHEMBL30752375 | 0.80 | BRD4 (0.33) | — | |
| SCHEMBL31438243 | 0.78 | KAT8 (0.34) | — | |
| SCHEMBL30752368 | 0.78 | CCR9 (0.33) | — | |
| SCHEMBL31438277 | 0.78 | SMO (0.36) | — | |
| SCHEMBL31438249 | 0.77 | — | — | |
| SCHEMBL31438302 | 0.75 | CCR9 (0.32) | — | |
| SCHEMBL31438262 | 0.75 | — | — | |
| SCHEMBL31438253 | 0.74 | CCR9 (0.31) | — | |
| SCHEMBL31438267 | 0.74 | MET (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4562003-A1 | NOVEL 7-SUBSTITUTED INDOLE SULFONAMIDE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2025-06-04 | — | — | EP | disclosed |
| CN-119585257-A | Novel 7-substituted indole sulfonamide derivatives | 豪夫迈·罗氏有限公司 | 2025-03-07 | — | — | CN | disclosed |
| WO-2024023128-A1 | NOVEL 7-SUBSTITUTED INDOLE SULFONAMIDE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2024-02-01 | — | — | WO | disclosed |