Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | CTSL | P07711 | 1/20 | 0.48 |
| ▸ | CTSB | P07858 | 1/20 | 0.48 |
| ▸ | CTSK | P43235 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | TLR4 | O00206 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | ACHE | P22303 | 2/20 | 0.45 |
| ▸ | CPB1 | P15086 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 5/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 5/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26503934 | 1.00 | ALDH1A1 (0.49) | ALDH1A1GAACTSLCTSBCTSK | |
| SCHEMBL9006197 | 1.00 | ALDH1A1 (0.49) | ALDH1A1GAACTSLCTSBCTSK | |
| SCHEMBL30404918 | 0.87 | ALDH1A1 (0.48) | ALDH1A1GAACTSLCTSBCTSK | |
| SCHEMBL25181699 | 0.87 | ALDH1A1 (0.48) | ALDH1A1GAACTSLCTSBCTSK | |
| SCHEMBL30752608 | 0.87 | ABCB1 (0.50) | ALDH1A1GAACTSLCTSBCTSK | |
| SCHEMBL29200858 | 0.86 | ALDH1A1 (0.50) | ALDH1A1GAACTSLCTSBCTSK | |
| SCHEMBL28661407 | 0.86 | TSHR (0.48) | ALDH1A1GAACTSLCTSBCTSK | |
| SCHEMBL29200855 | 0.86 | ALDH1A1 (0.50) | ALDH1A1GAACTSLCTSBCTSK | |
| SCHEMBL8990082 | 0.86 | ALDH1A1 (0.50) | ALDH1A1GAACTSLCTSBCTSK | |
| SCHEMBL16204631 | 0.86 | ABCB1 (0.51) | ALDH1A1GAACTSLCTSBCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260125386-A1 | COMPOSITIONS AND METHODS FOR INHIBITION OF KRAS | THERAS INC (US) | 2026-05-07 | — | — | US | disclosed |
| US-20260042764-A1 | COMPOSITIONS AND METHODS FOR INHIBITION OF KRAS | THERAS INC (US) | 2026-02-12 | — | — | US | disclosed |
| EP-4565579-A1 | COMPOSITIONS AND METHODS FOR INHIBITION OF KRAS | Theras, Inc. (US) | 2025-06-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260125386-A1 | COMPOSITIONS AND METHODS FOR INHIBITION OF KRAS | KRAS, NRAS, HRAS | ALDH1A1 3596/4885GAA 2625/4885CTSL 4024/4885 |
| US-20260042764-A1 | COMPOSITIONS AND METHODS FOR INHIBITION OF KRAS | KRAS, NRAS, HRAS | ALDH1A1 2677/4885GAA 3626/4885CTSL 3653/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.