Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | GLA | P06280 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | PDE2A | O00408 | 1/20 | 0.43 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acridine SCHEMBL9437430 | 0.77 | ALDH1A1 (0.58) | ALDH1A1HPGDKDM4EGLAGAA | |
| SCHEMBL30492958 | 0.76 | BRD4 (0.44) | ALDH1A1KDM4ECDK2ADORA2AADORA1 | |
| SCHEMBL1233156 | 0.76 | BRD4 (0.44) | ALDH1A1KDM4ECDK2ADORA2AADORA1 | |
| SCHEMBL11547422 | 0.75 | SRC (0.56) | ALDH1A1HPGDKDM4EGLAGAA | |
| SCHEMBL22717057 | 0.75 | KDM4E (0.36) | ALDH1A1HPGDKDM4EGLAGAA | |
| SCHEMBL10637092 | 0.75 | PDE3B (0.46) | ALDH1A1HPGDKDM4EGLAGAA | |
| Acridine SCHEMBL3851265 | 0.75 | ALDH1A1 (0.46) | ALDH1A1HPGDKDM4EGLAGAA | |
| SCHEMBL5721357 | 0.74 | ALDH1A1 (0.49) | ALDH1A1HPGDKDM4EGLAGAA | |
| SCHEMBL17265808 | 0.74 | ALDH1A1 (0.52) | ALDH1A1HPGDKDM4EGLAGAA | |
| SCHEMBL4132133 | 0.74 | KDM4E (0.52) | ALDH1A1HPGDKDM4EHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119798327-A | Novel quinoline imidazole skeleton chiral nitrogen phosphine ligand compound and synthetic method and application thereof | 浙江师范大学 | 2025-04-11 | — | — | CN | claimed |
| CN-114805354-A | Preparation method of quinoline-2-thioketone compound | 河南工程学院 | 2022-07-29 | — | — | CN | claimed |
| EP-0541153-A1 | 1,3-Dihydro-2H-imidazo[4,5-b]-quinolin-2-one derivatives as phosphodiesterase inhibitors | JANSSEN PHARMACEUTICA N.V. (BE) | 1993-05-12 | — | — | EP | claimed |
| US-5153104-A | Negative-acting photothermographic imaging systems comprising also a nitrate, an initiator, a leuco dye and a binder; colorfastness; clean background | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1992-10-06 | — | — | US | claimed |
| US-20260090195-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2026-03-26 | — | — | US | disclosed |
| CN-121270554-B | Quinoline imidazole derivative and preparation method and application thereof | 北京大学第一医院(北京大学第一临床医学院) | 2026-03-13 | — | — | CN | disclosed |
| CN-121270554-A | Quinoline imidazole derivative and preparation method and application thereof | 北京大学第一医院(北京大学第一临床医学院) | 2026-01-06 | — | — | CN | disclosed |
| CN-119798327-A | Novel quinoline imidazole skeleton chiral nitrogen phosphine ligand compound and synthetic method and application thereof | 浙江师范大学 | 2025-04-11 | — | — | CN | disclosed |
| CN-112778300-B | Organic compound and organic electroluminescent device containing the same | 北京鼎材科技有限公司 | 2024-02-02 | — | — | CN | disclosed |
| WO-2023168908-A1 | FUSED QUINONE OXIME IMIDAZOLE, ONIUM DERIVATIVE THEREOF, PREPARATION THEREFOR AND USE THEREOF | 上海交通大学 | 2023-09-14 | — | — | WO | disclosed |
| CN-114805354-A | Preparation method of quinoline-2-thioketone compound | 河南工程学院 | 2022-07-29 | — | — | CN | disclosed |
| CN-107207434-B | Organic molecules, in particular for use in optoelectronic devices | 西诺拉股份有限公司 | 2021-11-23 | — | — | CN | disclosed |
| EP-1599473-A1 | IMIDAZO 4,5-B QUINOLINE-DERIVATIVES AND THEIR USE AS NO-SYNTHASE INHIBITORS | ALTANA Pharma AG (DE) | 2005-11-30 | — | — | EP | disclosed |
| WO-2004076451-A1 | IMIDAZO[4,5-B]QUINOLINE-DERIVATIVES AND THEIR USE AS NO-SYNTHASE INHIBITORS | ALTANA PHARMA AG (DE) | 2004-09-10 | — | — | WO | disclosed |
| EP-0541153-A1 | 1,3-Dihydro-2H-imidazo[4,5-b]-quinolin-2-one derivatives as phosphodiesterase inhibitors | JANSSEN PHARMACEUTICA N.V. (BE) | 1993-05-12 | — | — | EP | disclosed |
| EP-0541153-A1 | 1,3-Dihydro-2H-imidazo[4,5-b]-quinolin-2-one derivatives as phosphodiesterase inhibitors | JANSSEN PHARMACEUTICA N.V. (BE) | 1993-05-12 | — | — | EP | disclosed |
| US-4965179-A | Silver halide color photographic material | FUJI PHOTO FILM CO., LTD. (JP) | 1990-10-23 | — | — | US | disclosed |
| US-4713316-A | INFRARED SENSITIZING DYES, MOBILE DYE PRECURSORS, ALKALI, SILVER HALIDE EMULSION | FUJI PHOTO FILM CO., LTD. (JP) | 1987-12-15 | — | — | US | disclosed |
| EP-0086230-B1 | MEROCYANINE-CYANINE-MEROCYANINE (MCM) ELECTRICALLY PHOTOSENSITIVE COLORANTS | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1987-01-07 | — | — | EP | disclosed |
| US-4463076-A | Merocyanine-cyanine-merocyanine (MCM) electrically photosensitive colorants for photoelectrophoretic imaging | EASTMAN KODAK COMPANY (US) | 1984-07-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260090195-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | LBR, GLRA1, GLRB | ALDH1A1 2803/4885HPGD 3302/4885KDM4E 3308/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.