Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KHK | P50053 | 1/20 | 0.40 |
| ▸ | ENPP1 | P22413 | 4/20 | 0.37 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2132096 | 0.85 | ACHE (0.38) | KDM4EMAPTGAAALDH1A1KHK | |
| SCHEMBL30753429 | 0.78 | KDM4E (0.46) | KDM4EMAPTGAAALDH1A1KHK | |
| SCHEMBL28117048 | 0.78 | ENPP1 (0.54) | KDM4EMAPTGAAALDH1A1KHK | |
| SCHEMBL30753419 | 0.78 | MAPT (0.42) | KDM4EMAPTGAAALDH1A1KHK | |
| SCHEMBL30753427 | 0.75 | MAPT (0.63) | KDM4EMAPTGAAALDH1A1KHK | |
| SCHEMBL13641617 | 0.75 | MAPT (0.63) | KDM4EMAPTGAAALDH1A1KHK | |
| SCHEMBL28910018 | 0.74 | MAPT (0.56) | KDM4EMAPTGAAALDH1A1MEN1 | |
| SCHEMBL28732554 | 0.73 | ENPP1 (0.44) | GAAENPP1ENPP3 | |
| SCHEMBL20047580 | 0.73 | GAA (0.38) | KDM4EMAPTGAAALDH1A1KHK | |
| SCHEMBL20047554 | 0.73 | GAA (0.38) | KDM4EMAPTGAAALDH1A1KHK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117466826-A | Preparation method of 2, 3-fluoroalkyl quinoxaline compound | 昆明理工大学 | 2024-01-30 | — | — | CN | disclosed |