Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | DEGS1 | O15121 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.41 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.41 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22580173 | 1.00 | PTGS1 (0.51) | PTGS1TDP1TSHRDEGS1SMN1; SMN2 | |
| SCHEMBL29395250 | 0.87 | TSHR (0.57) | PTGS1TDP1TSHRDEGS1SMN1; SMN2 | |
| SCHEMBL30753588 | 0.84 | HSD17B10 (0.54) | PTGS1TDP1TSHRDEGS1SMN1; SMN2 | |
| SCHEMBL22557436 | 0.84 | HSD17B10 (0.54) | PTGS1TDP1TSHRDEGS1SMN1; SMN2 | |
| SCHEMBL30648774 | 0.80 | RAB9A (0.48) | PTGS1TDP1TSHRDEGS1SMN1; SMN2 | |
| SCHEMBL26640280 | 0.80 | RAB9A (0.48) | PTGS1TDP1TSHRDEGS1SMN1; SMN2 | |
| SCHEMBL477342 | 0.79 | PTGS1 (0.55) | PTGS1TSHRDEGS1SMN1; SMN2RAB9A | |
| Alcohol SCHEMBL29043050 | 0.79 | PTK2 (0.56) | PTGS1TDP1SMN1; SMN2RAB9AL3MBTL1 | |
| SCHEMBL1674143 | 0.79 | DEGS1 (0.71) | TSHRDEGS1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL2944497 | 0.79 | TDP1 (0.71) | TDP1TSHRSMN1; SMN2RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113710664-B | JAK1 selective kinase inhibitors | 迪哲(江苏)医药股份有限公司 | 2024-01-26 | — | — | CN | disclosed |