Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoromethanesulfonic Acid SCHEMBL7644634 | 0.95 | PSMB8 (0.37) | PSMB8PSMB5 | |
| SCHEMBL3521342 | 0.85 | PSMB8 (0.37) | PSMB8PSMB5 | |
| SCHEMBL374355 | 0.85 | PSMB8 (0.37) | PSMB8PSMB5 | |
| Trifluoromethanesulfonic Acid SCHEMBL15049846 | 0.80 | PSMB8 (0.36) | PSMB8PSMB5 | |
| SCHEMBL10589660 | 0.79 | — | — | |
| SCHEMBL4987145 | 0.77 | PSMB8 (0.37) | PSMB8PSMB5 | |
| Trifluoromethanesulfonic Acid SCHEMBL7591458 | 0.77 | PSMB8 (0.34) | PSMB8PSMB5 | |
| SCHEMBL5898839 | 0.76 | PSMB8 (0.33) | PSMB8PSMB5 | |
| SCHEMBL3415993 | 0.75 | PSMB8 (0.36) | PSMB8PSMB5 | |
| SCHEMBL3893859 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7790864-B2 | Antibody to BACE455, an alternative splice variant of the human beta-secretase | EXONHIT THERAPEUTICS SA (FR) | 2010-09-07 | — | — | US | disclosed |
| US-7495093-B2 | Amplification and detection method | GEN-PROBE INCORPORATED (US) | 2009-02-24 | — | — | US | disclosed |
| US-7399852-B2 | Kits and reaction mixtures containing modified probe molecules | GEN-PROBE INCORPORATED (US) | 2008-07-15 | — | — | US | disclosed |
| US-20080090246-A1 | AMPLIFICATION AND DETECTION METHOD | GEN-PROBE INCORPORATED (US) | 2008-04-17 | — | — | US | disclosed |
| EP-0709466-B1 | Compositions and methods for the simultaneous detection and quantification of multiple specific nucleic acid sequences | GEN PROBE INC (US) | 2006-09-27 | — | — | EP | disclosed |
| EP-0912767-B1 | METHODS FOR DETECTING AND AMPLIFYING NUCLEIC ACID SEQUENCES USING MODIFIED OLIGONUCLEOTIDES HAVING INCREASED TARGET SPECIFIC TM | GEN PROBE INC (US) | 2006-09-13 | — | — | EP | disclosed |
| EP-1680505-A1 | BACE455, AN ALTERNATIVE SPLICE VARIANT OF THE HUMAN BETA-SECRETASE | Exonhit Therapeutics S.A. (FR) | 2006-07-19 | — | — | EP | disclosed |
| US-7070925-B1 | Method for determining the presence of an RNA analyte in a sample using a modified oligonucleotide probe | GEN-PROBE INCORPORATED (US) | 2006-07-04 | — | — | US | disclosed |
| US-6903206-B1 | Kits for amplifying target nucleic acid sequences using modified oligonucleotides | GEN-PROBE INCORPORATED (US) | 2005-06-07 | — | — | US | disclosed |
| WO-2005046726-A2 | COMBINATIONS FOR INHIBITING CELL GROWTH WHICH CONTAINS AN INHIBITOR OF HUMAN CK1 ALPHA ACTIVITY AND A RXR AGONIST | ALLERGAN, INC. (US) | 2005-05-26 | — | — | WO | disclosed |
| US-5576212-A | Oxidizing composition in powder form | BIOSENSOR LABORATORIES CO., LTD. (JP) | 1996-11-19 | — | — | US | disclosed |
| WO-1996013612-A2 | COMPOSITIONS AND METHODS FOR THE SIMULTANEOUS DETECTION AND QUANTIFICATION OF MULTIPLE SPECIFIC NUCLEIC ACID SEQUENCES | GEN-PROBE INCORPORATED (US) | 1996-05-09 | — | — | WO | disclosed |
| EP-0709466-A2 | Compositions and methods for the simultaneous detection and quantification of multiple specific nucleic acid sequences | GEN-PROBE INCORPORATED (US) | 1996-05-01 | — | — | EP | disclosed |
| EP-0309230-B1 | Homogeneous protection assay | GEN PROBE INC (US) | 1995-06-21 | — | — | EP | disclosed |
| EP-0638807-A1 | Protection assay | GEN-PROBE INCORPORATED (US) | 1995-02-15 | — | — | EP | disclosed |
| EP-0312248-B1 | Acridinium ester labelling and purification of nucleotide probes | GEN PROBE INC (US) | 1994-08-10 | — | — | EP | disclosed |
| US-5283174-A | Labeling binding partner of analyte with substance selectively susceptible to degradation | GEN-PROBE, INCORPORATED (US) | 1994-02-01 | — | — | US | disclosed |
| US-5185439-A | Mixing nucleic acid and labelling reagent to a specified concentration | GEN-PROBE INCORPORATED (US) | 1993-02-09 | — | — | US | disclosed |
| WO-1989002896-A1 | ACRIDINIUM ESTER LABELLING AND PURIFICATION OF NUCLEOTIDE PROBES | ML TECHNOLOGY VENTURES, L.P. (US) | 1989-04-06 | — | — | WO | disclosed |
| EP-0309230-A2 | Homogeneous protection assay | GEN-PROBE INCORPORATED (US) | 1989-03-29 | — | — | EP | disclosed |