SCHEMBL374355

SCHEMBL374355

C[n+]1c2ccccc2c(C(=O)O)c2c(-c3ccc(CCC(=O)ON4C(=O)CCC4=O)cc3)cccc21.O=S(=O)([O-])F

nearest known ligand 0.37

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PSMB8 P28062 1/20 0.37
PSMB5 P28074 1/20 0.37
HCAR2 Q8TDS4 1/20 0.31
FFAR1 O14842 4/20 0.30
FFAR4 Q5NUL3 4/20 0.30
PARL Q9H300 1/20 0.30
PTPN1 P18031 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3521342 1.00 PSMB8 (0.37) PSMB8PSMB5HCAR2FFAR1FFAR4
Trifluoromethanesulfonic Acid SCHEMBL15049846 0.94 PSMB8 (0.36) PSMB8PSMB5HCAR2FFAR1FFAR4
SCHEMBL4987145 0.92 PSMB8 (0.37) PSMB8PSMB5HCAR2FFAR1FFAR4
SCHEMBL3415993 0.89 PSMB8 (0.36) PSMB8PSMB5HCAR2FFAR1PARL
SCHEMBL6842917 0.88 PSMB8 (0.38) PSMB8PSMB5FFAR1FFAR4
SCHEMBL5446013 0.87 PSMB8 (0.36) PSMB8PSMB5
SCHEMBL3893859 0.86
SCHEMBL3075378 0.85 PSMB8 (0.38) PSMB8PSMB5
SCHEMBL9509305 0.84 PPARA (0.35)
SCHEMBL374354 0.81 KMT2A (0.33) PSMB8PSMB5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE39047-E1 Luminescence by reacting an acridinium ester with superoxide MITSUBISHI KAGAKU IATRON, INC. (JP) 2006-03-28 US claimed
JP-7278184-A None JP disclosed
US-10407740-B2 Oligonucleotides for use in determining the presence of Trichomonas vaginalis in a sample GEN-PROBE INCORPORATED (US) 2019-09-10 US disclosed
US-20180044739-A1 OLIGONUCLEOTIDES FOR USE IN DETERMINIING THE PRESENCE OF TRICHOMONAS VAGINALIS IN A SAMPLE BANK OF AMERICA, N.A., AS COLLATERAL AGENT 2018-02-15 US disclosed
US-9670554-B2 Capture probes for use in detecting the presence of Trichomonas vaginalis in a sample GEN-PROBE INCORPORATED (US) 2017-06-06 US disclosed
EP-2531515-B1 PROBES FOR DETECTING THE PRESENCE OF TROCHOMONAS VAGINALIS IN A SAMPLE GEN PROBE INC (US) 2015-10-21 EP disclosed
EP-2027293-B1 METHOD OF LYSING MYCOBACTERIUM AND AMPLIFYING ITS NUCLEIC ACID GEN PROBE INC (US) 2014-11-19 EP disclosed
US-20140335519-A1 CAPTURE PROBES FOR USE IN DETECTING THE PRESENCE OF TRICHOMONAS VAGINALIS IN A SAMPLE GEN-PROBE INCORPORATED 2014-11-13 US disclosed
US-8790879-B2 Probes for detecting the presence of Trichomonas vaginalis in a sample GEN-PROBE INCORPORATED (US) 2014-07-29 US disclosed
EP-2292793-B1 Compositions, methods and kits for determining the presence of Trichomonas Vaginalis in a test sample GEN PROBE INC (US) 2013-12-04 EP disclosed
WO-1996041178-A1 MICELLE PROTECTION ASSAY GEN-PROBE INCORPORATED (US) 1996-12-19 WO disclosed
EP-0522677-B1 Method of measuring concentration of immunoreactant using electrochemiluminescence TDK CORP (JP) 1996-12-18 EP disclosed
EP-0747488-A1 Methods and kits for determining pre-amplification levels of a nucleic acid target sequence from post-amplification levels of product GEN-PROBE INCORPORATED (US) 1996-12-11 EP disclosed
EP-0747701-A1 Micelle protection assay GEN-PROBE INCORPORATED (US) 1996-12-11 EP disclosed
EP-0478626-B1 DETECTING OR QUANTIFYING MULTIPLE ANALYTES USING LABELLING TECHNIQUES GEN PROBE INC (US) 1996-01-17 EP disclosed
JP-H07278184-A STABILIZATION OF ANTIGEN OR ANTIBODY LABELED WITH ACRIDINIUM DERIVATIVE KYOWA MEDEX CO LTD 1995-10-24 JP disclosed
EP-0522677-A1 Method of measuring concentration of immunoreactant using electrochemiluminescence TDK Corporation (JP) 1993-01-13 EP disclosed
EP-0519070-A1 METHOD OF JUDGING TYPE OF HUMAN LEUKOCYTE ANTIGEN Chugai Seiyaku Kabushiki Kaisha (JP) 1992-12-23 EP disclosed
EP-0478626-A1 DETECTING OR QUANTIFYING MULTIPLE ANALYTES USING LABELLING TECHNIQUES. UNIV WALES MEDICINE (GB) 1992-04-08 EP disclosed
WO-1991000511-A1 DETECTING OR QUANTIFYING MULTIPLE ANALYTES USING LABELLING TECHNIQUES UNIVERSITY OF WALES COLLEGE OF MEDICINE (GB) 1991-01-10 WO disclosed