SCHEMBL30754137

SCHEMBL30754137

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nearest known ligand 0.42

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
QRFPR Q96P65 5/20 0.42
TGFBR1 P36897 3/20 0.42
MME P08473 6/20 0.39
NMT2 O60551 2/20 0.38
NMT1 P30419 2/20 0.38
TERT O14746 1/20 0.38
SLC15A2 Q16348 1/20 0.34
OPRM1 P35372 1/20 0.34
OPRD1 P41143 1/20 0.34
OPRK1 P41145 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29987730 1.00 QRFPR (0.42) QRFPRTGFBR1MMENMT2NMT1
SCHEMBL29547981 1.00 QRFPR (0.42) QRFPRTGFBR1MMENMT2NMT1
SCHEMBL29410190 0.98 TGFBR1 (0.43) QRFPRTGFBR1MMENMT2NMT1
SCHEMBL31383401 0.97 QRFPR (0.41) QRFPRTGFBR1MMENMT2NMT1
SCHEMBL30851114 0.97 QRFPR (0.41) QRFPRTGFBR1MMENMT2NMT1
SCHEMBL29828566 0.97 QRFPR (0.41) QRFPRTGFBR1MMENMT2NMT1
SCHEMBL30220824 0.95 QRFPR (0.42) QRFPRTGFBR1MMENMT2NMT1
SCHEMBL31424011 0.94 TGFBR1 (0.40) QRFPRTGFBR1MMENMT2NMT1
SCHEMBL30956647 0.94 TGFBR1 (0.40) QRFPRTGFBR1MMENMT2NMT1
SCHEMBL30956646 0.94 TGFBR1 (0.40) QRFPRTGFBR1MMENMT2NMT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240035060-A1 METHODS AND SYSTEMS FOR CELL-FREE BIODISCOVERY OF NATURAL PRODUCTS SYNVITROBIO, INC. 2024-02-01 US claimed
US-20240035060-A1 METHODS AND SYSTEMS FOR CELL-FREE BIODISCOVERY OF NATURAL PRODUCTS SYNVITROBIO, INC. 2024-02-01 US disclosed