SCHEMBL30754191

SCHEMBL30754191

Fc1c(Cc2ccccc2)ccnc1-c1ccccn1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 5/20 0.46
RAB9A P51151 5/20 0.46
SMN1; SMN2 Q16637 4/20 0.46
ALDH1A1 P00352 3/20 0.46
MCL1 Q07820 4/20 0.43
GABRA1 P14867 1/20 0.40
GABRB2 P47870 1/20 0.40
METAP1 P53582 2/20 0.39
KDM4E B2RXH2 1/20 0.39
LMNA P02545 1/20 0.39
CYP1A2 P05177 1/20 0.39
POLB P06746 1/20 0.39
CCR1 P32246 1/20 0.39
CCR5 P51681 1/20 0.39
CCR8 P51685 1/20 0.39
BLM P54132 1/20 0.39
HIF1A Q16665 1/20 0.39
DOHH Q9BU89 1/20 0.39
P4HTM Q9NXG6 1/20 0.39
NTRK1 P04629 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28320236 0.83 NPC1 (0.47) NPC1RAB9ASMN1; SMN2ALDH1A1MCL1
SCHEMBL6888804 0.80 LIMK2 (0.51) NPC1RAB9ASMN1; SMN2ALDH1A1MCL1
Hydrochloric Acid SCHEMBL27589867 0.79 LIMK2 (0.50) NPC1RAB9ASMN1; SMN2ALDH1A1MCL1
SCHEMBL30739256 0.74 KDM4E (0.50) NPC1RAB9ASMN1; SMN2ALDH1A1MCL1
SCHEMBL8131574 0.74 KDM4E (0.50) NPC1RAB9ASMN1; SMN2ALDH1A1MCL1
SCHEMBL30435128 0.71 KDM4E (0.53) NPC1RAB9ASMN1; SMN2ALDH1A1MCL1
SCHEMBL31305611 0.70 KDM4E (0.45) NPC1RAB9ASMN1; SMN2ALDH1A1MCL1
SCHEMBL31040494 0.69 NPC1 (0.49) NPC1RAB9ASMN1; SMN2MCL1METAP1
SCHEMBL3886009 0.67 MET (0.49) NPC1RAB9ASMN1; SMN2ALDH1A1MET
SCHEMBL28594190 0.67 MEN1 (0.39) ALDH1A1LMNACYP1A2HIF1AMET

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112236421-B Pyrazole derivatives and pest control agents 组合化学工业株式会社 2023-12-26 CN disclosed