Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PABPC1 | P11940 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27864973 | 0.71 | PDPK1 (0.37) | KDM4EALDH1A1LMNAADORA2AADORA1 | |
| SCHEMBL31291363 | 0.70 | — | — | |
| SCHEMBL25859151 | 0.69 | — | — | |
| SCHEMBL31314104 | 0.69 | — | — | |
| SCHEMBL27686042 | 0.65 | KDM4E (0.32) | KDM4E | |
| SCHEMBL27906087 | 0.65 | — | — | |
| SCHEMBL25167879 | 0.65 | ENPP1 (0.38) | KDM4EALDH1A1 | |
| SCHEMBL21963087 | 0.64 | ENPP3 (0.35) | ALDH1A1 | |
| SCHEMBL27955980 | 0.61 | UHRF1 (0.34) | KDM4E | |
| SCHEMBL14166499 | 0.61 | NQO1 (0.33) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117460718-A | Triazine derivatives and their use in the treatment of cancer | 豪夫迈·罗氏有限公司 | 2024-01-26 | — | — | CN | disclosed |