SCHEMBL30754397

SCHEMBL30754397

COc1cc(C2CO2)ccc1O

nearest known ligand 0.71

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PPARD Q03181 4/20 0.71
PPARG P37231 3/20 0.71
PTPN1 P18031 3/20 0.71
ALOX5 P09917 1/20 0.71
CYP3A4 P08684 1/20 0.63
CA2 P00918 2/20 0.59
NR3C1 P04150 2/20 0.59
QDPR P09417 2/20 0.58
PPARA Q07869 1/20 0.56
TSHR P16473 1/20 0.54
POLB P06746 1/20 0.52
CYP1A1 P04798 1/20 0.52
CYP1A2 P05177 1/20 0.52
CYP1B1 Q16678 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13317169 1.00 PPARD (0.71) PPARDPPARGPTPN1ALOX5CYP3A4
SCHEMBL901629 0.83 ACHE (0.57) PPARDPPARGPTPN1ALOX5NR3C1
(+)-Pinoresinol SCHEMBL13506178 0.83 PPARD (1.00) PPARDPPARGPTPN1ALOX5CYP3A4
(+)-Pinoresinol SCHEMBL3497226 0.83 PPARD (1.00) PPARDPPARGPTPN1ALOX5CYP3A4
(+)-Pinoresinol SCHEMBL13322131 0.83 PPARD (1.00) PPARDPPARGPTPN1ALOX5CYP3A4
(+/-)-Pinoresinol SCHEMBL122106 0.83 PPARD (1.00) PPARDPPARGPTPN1ALOX5CYP3A4
Pinoresinol SCHEMBL10019016 0.83 PPARD (1.00) PPARDPPARGPTPN1ALOX5CYP3A4
(+)-Pinoresinol SCHEMBL122105 0.83 PPARD (1.00) PPARDPPARGPTPN1ALOX5CYP3A4
(+)-Pinoresinol SCHEMBL15481159 0.83 PPARD (1.00) PPARDPPARGPTPN1ALOX5CYP3A4
Pinoresinol SCHEMBL31202559 0.83 PPARD (1.00) PPARDPPARGPTPN1ALOX5CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117603897-A Method for producing 3, 4-dihydroxyphenylacetic acid 杭州唯铂莱生物科技有限公司 2024-02-27 CN disclosed