Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 4/20 | 0.51 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
| ▸ | HTR6 | P50406 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | HTR1D | P28221 | 3/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR1E | P28566 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | HTR5A | P47898 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 3/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26688606 | 1.00 | HTR1A (0.51) | HTR1ATRPM8TRPV1HTR6HDAC1 | |
| SCHEMBL25244986 | 0.88 | HTR1A (0.60) | HTR1AHTR6HTR2AHTR1DDRD1 | |
| SCHEMBL31105616 | 0.82 | HTR1A (0.45) | HTR1ATRPM8TRPV1HTR6HDAC1 | |
| SCHEMBL25239276 | 0.81 | HTR1A (0.52) | HTR1AHTR6HTR2AHTR1DDRD1 | |
| SCHEMBL31105724 | 0.81 | HTR1A (0.79) | HTR1ATRPM8TRPV1HTR6HDAC1 | |
| SCHEMBL25029867 | 0.80 | HTR1A (0.57) | HTR1AHTR6HTR2AHTR1DDRD1 | |
| SCHEMBL25029851 | 0.77 | HTR1A (0.72) | HTR1AHTR6HTR2AHTR1DDRD1 | |
| SCHEMBL25008690 | 0.77 | HTR1A (0.50) | HTR1AHTR6HDAC1KCNH2HTR2A | |
| SCHEMBL31077923 | 0.76 | HTR1A (0.56) | HTR1AHTR6HTR2AHTR1DDRD1 | |
| SCHEMBL25288798 | 0.76 | HTR1A (0.56) | HTR1AHTR6HTR2AHTR1DDRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023225043-A1 | TRICYCLIC AND TETRACYCLIC SEROTONIN RECEPTOR MODULATORS AND METHODS OF MAKING AND USING THE SAME | KULEON LLC (US) | 2023-11-23 | — | — | WO | disclosed |