Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 11/20 | 0.97 |
| ▸ | NPC1 | O15118 | 10/20 | 0.97 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.80 |
| ▸ | TP53 | P04637 | 1/20 | 0.80 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.80 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.74 |
| ▸ | PGR | P06401 | 2/20 | 0.71 |
| ▸ | HTT | P42858 | 1/20 | 0.71 |
| ▸ | MEN1 | O00255 | 2/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.70 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.69 |
| ▸ | CASP3 | P42574 | 1/20 | 0.68 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.68 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 1/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.65 |
| ▸ | F10 | P00742 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4963650 | 0.98 | RAB9A (1.00) | RAB9ANPC1SMN1; SMN2TP53ALOX15 | |
| Hydrochloric Acid SCHEMBL29693066 | 0.97 | RAB9A (0.97) | RAB9ANPC1SMN1; SMN2TP53ALOX15 | |
| Nitrogen SCHEMBL28090858 | 0.93 | RAB9A (0.90) | RAB9ANPC1SMN1; SMN2TP53ALOX15 | |
| SCHEMBL11548282 | 0.93 | RAB9A (0.90) | RAB9ANPC1SMN1; SMN2TP53ALOX15 | |
| SCHEMBL5340339 | 0.92 | RAB9A (0.88) | RAB9ANPC1SMN1; SMN2TP53ALOX15 | |
| SCHEMBL2919439 | 0.91 | RAB9A (0.87) | RAB9ANPC1SMN1; SMN2TP53ALOX15 | |
| SCHEMBL28185905 | 0.91 | RAB9A (0.85) | RAB9ANPC1SMN1; SMN2TP53ALOX15 | |
| SCHEMBL31179828 | 0.89 | KCNK9 (0.83) | RAB9ANPC1SMN1; SMN2TP53ALOX15 | |
| SCHEMBL6799157 | 0.89 | RAB9A (1.00) | RAB9ANPC1SMN1; SMN2TP53ALOX15 | |
| SCHEMBL12010917 | 0.89 | RAB9A (0.82) | RAB9ANPC1SMN1; SMN2TP53ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117466799-A | Preparation method of N-substituted phthalimide compound | 西北师范大学 | 2024-01-30 | — | — | CN | claimed |
| CN-117466799-B | N-substituted phthalic acid diamide preparation method of imine compound | 西北师范大学 | 2024-12-24 | — | — | CN | disclosed |
| CN-117466799-A | Preparation method of N-substituted phthalimide compound | 西北师范大学 | 2024-01-30 | — | — | CN | disclosed |